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Eleven people have been charged in connection with an alleged plot to blow up several transatlantic airliners.
Eight have been charged with conspiracy to murder and preparing acts of terrorism.
Two are accused of failing to disclose information and a 17-year-old faces a charge of possessing articles useful to a person preparing acts of terrorism.
One woman has been freed without charge and eleven people remain in custody, the Crown Prosecution Service said.
Ahmed Abdullah Ali, Tanvir Hussain, Umar Islam, Arafat Waheed Khan, Assad Ali Sarwar, Adam Khatib, Ibrahim Savant and Waheed Zaman are all charged with conspiracy to murder and with preparing acts of terrorism under section five of the Terrorism Act 2006.
The threat from terrorism is real. It is here, it is deadly and it is enduring
Peter Clarke, Metropolitan Police
Charges in full
Full police statement
The Met's Deputy Assistant Commissioner Peter Clarke told journalists bomb making equipment, including chemicals and electrical components, had been found during the investigation into the alleged plot.
He added a number of video recordings known as "martyrdom videos" had also been recovered.
Mr Clarke said: "I would like to reassure the public that we are doing everything we can to keep you safe so that you can live your lives without being in constant fear.
"The threat from terrorism is real. It is here, it is deadly and it is enduring.
"As we all look for explanations, we cannot afford to be complacent and ignore the reality of what we face".
The investigation is "immense" say police
He added:
"However the investigation is far from complete. The scale is immense, inquiries will span the globe.
"The enormity of the alleged plot will be matched only by our determination to follow every lead and line of inquiry."
An initial 24 people were arrested following police raids in Walthamstow, east London, High Wycombe in Buckinghamshire and Birmingham on 10 August.
Security at airports was increased, causing widespread flight cancellations in the UK for several days.
Scotland Yard said that those charged would appear at City of Westminster Magistrates' Court in London on Tuesday.
'Immense' investigation
Mr Clarke said the investigation of the material seized by police was likely to take months.
In a highly unusual development, Mr Clarke went into significant detail about the evidence so far uncovered by police inquiries. These included:
69 searches of houses, flats and business premises, vehicles and open spaces
Searches had found more than 400 computers, 200 mobile telephones and 8,000 computer media items such as memory sticks, CDs and DVDs
Police experts have removed 6,000 gigabytes of data from the seized computers
Bomb making equipment, including chemicals and electrical components seized, police say
A number of video recordings recovered.
At the news conference, Susan Hemming, head of the Crown Prosecution Service Counter Terrorism Division, said she had been working with Scotland Yard officers for the past eight days.
"We have been carefully examining and assessing the evidence against each individual with the assistance of anti-terrorist officers in order to come to charging decisions at the earliest practicable opportunity."
She added that the position of the 11 people still in custody would be "assessed on a regular basis".
"We cannot yet make a decision about whether further charges will follow or if a further application for detention will be made on Wednesday, as the evidential picture is continuously developing."